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In situ hybridization (ISH) is a type of hybridization that uses a labeled complementary DNA, RNA or modified nucleic acids strand (i.e., probe) to localize a specific DNA or RNA sequence in a portion or section of tissue (in situ), or, if the tissue is small enough (e.g., plant seeds, Drosophila embryos), in the entire tissue (whole mount ISH), in cells, and in circulating tumor cells (CTCs).
In situ hybridization is used to reveal the location of specific nucleic acid sequences on chromosomes or in tissues, a crucial step for understanding the organization, regulation, and function of genes. The key techniques currently in use include: in situ hybridization to mRNA with oligonucleotide and RNA probes (both radio-labelled and hapten-labelled); analysis with light and electron microscopes; whole mount in situ hybridization; double detection of RNAs and RNA plus protein; and fluorescent in situ hybridization to detect chromosomal sequences. DNA ISH can be used to determine the structure of chromosomes. Fluorescent DNA ISH (FISH) can, for example, be used in medical diagnostics to assess chromosomal integrity. RNA ISH (RNA in situ hybridization) is used to measure and localize RNAs (mRNAs, lncRNAs, and miRNAs) within tissue sections, cells, whole mounts, and circulating tumor cells (CTCs).
In 2021, the global In-situ Hybridization (ISH) market size will be US$ XX million and it is expected to reach US$ XX million by the end of 2027, with a CAGR of XX% during 2021-2027.
This report focuses on the global In-situ Hybridization (ISH) status, future forecast, growth opportunity, key market, and key players. The study objectives are to present the In-situ Hybridization (ISH) development in North America, Europe, Japan, China, Southeast Asia, India, etc.
Global In-situ Hybridization (ISH) Scope and Market Size
In-situ Hybridization (ISH) market is segmented by company, region (country), by Type, and by Application. Players, stakeholders, and other participants in the global In-situ Hybridization (ISH) market will be able to gain the upper hand as they use the report as a powerful resource. The segmental analysis focuses on revenue and forecast by Type and by Application in terms of revenue and forecast for the period 2016-2027.
Segment by Type
Fluorescence In Situ Hybridization (FISH)
Chromogenic In Situ Hybridization
Segment by Application
Molecular Diagnostic Laboratories
Pharmaceutical & Biotechnology Companies
Contract Research Organizations (CROs)
Academic & Research Institutions
By Region
North America
Europe
Japan
China
Southeast Asia
India
By Company
ABBott Laboratories
F.Hoffmann-La Roche
Thermofisher Scientific
Merck
Agilent Technologies
Perkin Elmer
Danaher Corporation
Exiqon
Biogenex Laboratories
Advanced Cell Diagnostics
Bio SB
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